86879-39-2

86879-39-2 structure

Name: CMPF
Chemical Name: 2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid
CAS Number: 86879-39-2
Molecular Formula: C₁₂H₁₆O₅
Molecular Weight: 240.252
Catalog: Research Areas Metabolic Disease
Create Date: 2018-06-26 17:06:03
Modify Date: 2024-01-17 12:20:58
CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].

Name	2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid
Synonyms	2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid Cmpfpa 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC C1F 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid 2-(2-Carboxyethyl)-4-methyl-5-propyl-3-furoic acid 2-Furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-

Description	CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Prentice KJ, et al. The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction. Cell Metab. 2014 Apr 1;19(4):653-66. [2]. Prentice KJ, et al. CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. EBioMedicine. 2018 Jan;27:200-213.