CMPF

Modify Date: 2024-01-17 12:20:58

CMPF Structure
CMPF structure
Common Name CMPF
CAS Number 86879-39-2 Molecular Weight 240.252
Density 1.2±0.1 g/cm3 Boiling Point 404.0±45.0 °C at 760 mmHg
Molecular Formula C12H16O5 Melting Point N/A
MSDS N/A Flash Point 198.1±28.7 °C

 Use of CMPF


CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].

 Names

Name 2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid
Synonym More Synonyms

 CMPF Biological Activity

Description CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice[1][2].
Related Catalog
References

[1]. Prentice KJ, et al. The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction. Cell Metab. 2014 Apr 1;19(4):653-66.  

[2]. Prentice KJ, et al. CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis. EBioMedicine. 2018 Jan;27:200-213.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 404.0±45.0 °C at 760 mmHg
Molecular Formula C12H16O5
Molecular Weight 240.252
Flash Point 198.1±28.7 °C
Exact Mass 240.099777
PSA 87.74000
LogP 2.63
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.532

 Synonyms

2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid
Cmpfpa
3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC
C1F
3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid
2-(2-Carboxyethyl)-4-methyl-5-propyl-3-furoic acid
2-Furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-
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