Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: thenalidine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

86-12-4

86-12-4 structure

Name: thenalidine
Chemical Name: 1-methyl-N-phenyl-N-(thiophen-2-ylmethyl)piperidin-4-amine
CAS Number: 86-12-4
Molecular Formula: C₁₇H₂₂N₂S
Molecular Weight: 286.43500
Catalog: API Antiallergic Allergic reaction medium blocker
Create Date: 2018-02-26 08:00:00
Modify Date: 2024-01-22 16:21:49

Name	1-methyl-N-phenyl-N-(thiophen-2-ylmethyl)piperidin-4-amine
Synonyms	N-(1-Methyl-[4]piperidyl)-N-[2]thienylmethyl-anilin 1-Methyl-4-N-2-thenylanilinopiperidine Sandosten (4-Amino-1-methyl-N'-phenyl-N'-then-2-yl-piperidin-tartrat) Sanbosten Tenalidina [INN-Spanish] N-(1-methyl-[4]piperidyl)-N-[2]thienylmethyl-aniline Thenalidinum Thenalidinum [INN-Latin] Tenalidina thenalidine 1-Methyl-4-<phenyl-<2-thenyl-amino>-piperidin Thenophenopiperidine N-Methyl-4-(N-thenyl-2-anilino)-piperidin Thenaldine 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine

Density	1.14g/cm3
Boiling Point	413.9ºC at 760 mmHg
Melting Point	95-97°
Molecular Formula	C₁₇H₂₂N₂S
Molecular Weight	286.43500
Flash Point	204.1ºC
Exact Mass	286.15000
PSA	34.72000
LogP	3.78680
Index of Refraction	1.619

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN1400000

CHEMICAL NAME :: Piperidine, 1-methyl-4-(N-2-thenylanilino)-

CAS REGISTRY NUMBER :: 86-12-4

BEILSTEIN REFERENCE NO. :: 0244448

LAST UPDATED :: 199709

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C17-H22-N2-S

MOLECULAR WEIGHT :: 286.47

WISWESSER LINE NOTATION :: T6NTJ A1 DNR&1- BT5SJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1060 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANAEA3 Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- 1943- Volume(issue)/page/year: 21,233,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANAEA3 Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- 1943- Volume(issue)/page/year: 21,233,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANAEA3 Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- 1943- Volume(issue)/page/year: 21,233,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANAEA3 Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- 1943- Volume(issue)/page/year: 21,233,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MEWEAC Medizinische Welt. (F.K. Schattauer Verlag, Postfach 2945, D-7000 Stuttgart 1, Fed. Rep. Ger.) V.1-18, 1927-1944; V.1- 1950- Volume(issue)/page/year: 17,2791,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ANAEA3 Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- 1943- Volume(issue)/page/year: 21,233,1963

HS Code	2934999090

108-86-1

100051-94-3

86-12-4

Literature: Sandoz Patent: US2757175 , 1954 ; Full Text Show Details Sandoz Patent: DE1018420 , 1954 ;

765-50-4

22261-94-5

86-12-4

Literature: Sandoz Patent: US2717251 , 1952 ; Full Text Show Details Sandoz Patent: DE961348 , 1952 ;

Precursor 4
108-86-1 100051-94-3 765-50-4 22261-94-5
DownStream 1
6846-13-5

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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