439904-33-3

439904-33-3 structure

Name: KOdiA-PC
Chemical Name: KOdiA-PC
CAS Number: 439904-33-3
Molecular Formula: C₃₂H₅₈NO₁₁P
Molecular Weight: 663.777
Catalog: Research Areas Others
Create Date: 2017-09-27 04:38:16
Modify Date: 2024-02-28 12:22:29
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

Name	KOdiA-PC
Synonyms	(2R)-2-{[(6E)-7-Carboxy-5-oxo-6-heptenoyl]oxy}-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate Ethanaminium, 2-[[[(2R)-2-[[(6E)-7-carboxy-1,5-dioxo-6-hepten-1-yl]oxy]-3-[(1-oxohexadecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt

Description	Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.
Related Catalog	Research Areas >> Others