Name | (E)-N-[2-(2-cyclohexylethylsulfanyl)ethyl]dec-2-enamide |
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Synonyms |
2-Decenamide,N-(2-((2-cyclohexylethyl)thio)ethyl)-,(E)
2-(E-2-decenoylamino)ethyl 2-cyclohexylethyl sulfide 2-Deces 2-(2-Decenoylamino)ethyl-2-(cyclohexylethyl)sulfide 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide |
Description | 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress. |
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Related Catalog | |
Target |
PGE2 PGI2 PLA2 |
In Vivo | 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice[1]. |
References |
Density | 0.954g/cm3 |
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Boiling Point | 503.3ºC at 760 mmHg |
Molecular Formula | C20H37NOS |
Molecular Weight | 339.57900 |
Flash Point | 258.2ºC |
Exact Mass | 339.26000 |
PSA | 57.89000 |
LogP | 6.56320 |
Vapour Pressure | 2.93E-10mmHg at 25°C |
Index of Refraction | 1.498 |
Precursor 3 | |
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DownStream 0 |