1256963-02-6
1256963-02-6 structure
- Name: Ribociclib
- Chemical Name: 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
- CAS Number: 1256963-02-6
- Molecular Formula: C22H29ClN8
- Molecular Weight: 440.972
- Catalog: API Antineoplastic agents Other antineoplastic agents
- Create Date: 2018-05-03 08:00:00
- Modify Date: 2025-08-26 05:23:59
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CDK4-IN-1 is a selective inhibitor of cyclin-dependent kinase 4.
| Name | 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine |
|---|---|
| Synonyms |
2-Pyrimidinamine, 4-[3-chloro-5-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-
4-(5-chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine 4-(3-Chloro-5-isopropyl-1H-pyrazol-4-yl)-N-{5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl}-2-pyrimidinamine 2-Pyrimidinamine, 4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]- 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-{5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl}-2-pyrimidinamine QC-9704 LEE011 Ribociclib |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 679.3±65.0 °C at 760 mmHg |
| Molecular Formula | C22H29ClN8 |
| Molecular Weight | 440.972 |
| Flash Point | 364.6±34.3 °C |
| Exact Mass | 440.220367 |
| PSA | 85.86000 |
| LogP | 3.19 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.644 |
| Storage condition | 2-8°C |
| Hazard Codes | Xi |
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