Name | diethyl 2-[(4-bromophenyl)methyl]propanedioate |
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Synonyms |
Diethyl (4-bromobenzyl)malonate
Diethyl-(4-brombenzyl)malonat Propanedioic acid, 2-[(4-bromophenyl)methyl]-, diethyl ester |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 375.7±27.0 °C at 760 mmHg |
Molecular Formula | C14H17BrO4 |
Molecular Weight | 329.186 |
Flash Point | 181.0±23.7 °C |
Exact Mass | 328.031006 |
PSA | 52.60000 |
LogP | 3.53 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |
Index of Refraction | 1.523 |
~82% 70146-78-0 |
Literature: VITAE PHARMACEUTICALS, INC.; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; CACATIAN, Salvacion; CLAREMON, David, A.; DILLARD, Lawrence, W.; FUCHS, Klaus; HEINE, Niklas; JIA, Lanqi; LEFTHERIS, Katerina; MCKEEVER, Brian; MORALES-RAMOS, Angel; SINGH, Suresh; VENKATRAMAN, Shankar; WU, Guosheng; WU, Zhongren; XU, Zhenrong; YUAN, Jing; ZHENG, Yajun Patent: WO2010/105179 A2, 2010 ; Location in patent: Page/Page column 76 ; WO 2010/105179 A2 |
~49% 70146-78-0 |
Literature: Ward, Richard A.; Brassington, Claire; Breeze, Alexander L.; Caputo, Alessandro; Critchlow, Susan; Davies, Gareth; Goodwin, Louise; Hassall, Giles; Greenwood, Ryan; Holdgate, Geoffrey A.; Mrosek, Michael; Norman, Richard A.; Pearson, Stuart; Tart, Jonathan; Tucker, Julie A.; Vogtherr, Martin; Whittaker, David; Wingfield, Jonathan; Winter, Jon; Hudson, Kevin Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 3285 - 3306 |
~% 70146-78-0 |
Literature: Huang, Wen; Zheng, Pengzhi; Zhang, Zhengxing; Liu, Rutting; Chen, Zhenxia; Zhou, Xigeng Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6845 - 6848 |
~% 70146-78-0 |
Literature: Kuwabara, Kenji; Aoki, Tomiyoshi Patent: US2003/166697 A1, 2003 ; |
Precursor 4 | |
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DownStream 10 | |