895542-09-3
895542-09-3 structure
- Name: Trifarotene
- Chemical Name: 4-[3-(3-tert-butyl-4-pyrrolidin-1-ylphenyl)-4-(2-hydroxyethoxy)phenyl]benzoic acid
- CAS Number: 895542-09-3
- Molecular Formula: C29H33NO4
- Molecular Weight: 459.577
- Catalog: Signaling Pathways Metabolic Enzyme/Protease RAR/RXR
- Create Date: 2018-08-29 16:37:34
- Modify Date: 2024-01-04 07:48:14
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Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively.
| Name | 4-[3-(3-tert-butyl-4-pyrrolidin-1-ylphenyl)-4-(2-hydroxyethoxy)phenyl]benzoic acid |
|---|---|
| Synonyms |
4'-(2-Hydroxyethoxy)-3''-(2-methyl-2-propanyl)-4''-(1-pyrrolidinyl)-1,1':3',1''-terphenyl-4-carboxylic acid
[1,1':3',1''-Terphenyl]-4-carboxylic acid, 3''-(1,1-dimethylethyl)-4'-(2-hydroxyethoxy)-4''-(1-pyrrolidinyl)- Trifarotene CD5789 UNII-0J8RN2W0HK |
| Description | Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively. |
|---|---|
| Related Catalog | |
| Target |
Kdapp: 2 nM (RARγ), 15 nM (RARβ), 500 nM (RARα)[1] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 641.9±55.0 °C at 760 mmHg |
| Molecular Formula | C29H33NO4 |
| Molecular Weight | 459.577 |
| Flash Point | 342.0±31.5 °C |
| Exact Mass | 459.240967 |
| PSA | 70.00000 |
| LogP | 6.27 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.599 |
| Storage condition | 2-8℃ |