863918-78-9

863918-78-9 structure

Name: Methoxy-X04
Chemical Name: methoxy-X04
CAS Number: 863918-78-9
Molecular Formula: C₂₃H₂₀O₃
Molecular Weight: 344.40300
Catalog: Research Areas Others
Create Date: 2016-02-20 19:56:11
Modify Date: 2024-01-11 19:48:18
Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques.

Name	methoxy-X04
Synonyms	m-methoxy-trans-β-nitrostyrene 1,4-bis (4''-hydroxystyrl)-2-methoxybenzene (E,E)-1-methoxy-2,5-bis(4-hydroxy)styrylbenzene

Description	Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques.
Related Catalog	Research Areas >> Others
References	[1]. Klunk WE, Bacskai BJ, Mathis CA, et al. Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J Neuropathol Exp Neurol. 2002;61(9):797-805. doi:10.1093/jnen/61.9.797 [2]. Bisht K, El Hajj H, Savage JC, Sánchez MG, Tremblay MÈ. Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques. J Vis Exp. 2016;(112):54060. Published 2016 Jun 1.