64519-82-0

64519-82-0 structure

Name: glucosylmannitol
Chemical Name: Isomalt
CAS Number: 64519-82-0
Molecular Formula: C₁₂H₂₄O₁₁
Molecular Weight: 344.312
Catalog: Signaling Pathways Metabolic Enzyme/Protease Lactate Dehydrogenase
Create Date: 2018-07-25 17:50:38
Modify Date: 2024-01-04 00:20:08
Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].

Name	Isomalt
Synonyms	1-O-α-D-Glucopyranosyl-D-mannitol Plaltinitol PALATINOL ISOMALT USP MFCD00190708 PALATINIT hydrogenated isomaltulose glucosylmannitol Isomaltitol EINECS 203-252-1 D-mannitol, 1-O-a-D-glucopyranosyl- 1-O-a-D-glucopyranosyl-D-mannitol D-Mannitol, 1-O-α-D-glucopyranosyl- PALATINITOL

Description	Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase Research Areas >> Metabolic Disease
In Vivo	The chronic toxicity of orally administered isomalt as a part of diet has been studied in animals and it was found to be a safe substance. It did not affect the mortality rate of the animals, and there was no evidence of carcinogenicity, or adverse effects on fertility, reproductive performance or development[1].
References	[1]. Tuderman AK, et al. Isomalt and its diastereomer mixtures as stabilizing excipients with freeze-dried lactate dehydrogenase. Int J Pharm. 2018 Mar 1;538(1-2):287-295.

CHEMICAL NAME :: D-Glucitol, 6-O-alpha-D-glucopyranosyl-, mixed with 1-O-alpha-D-glucopyranosyl-D-mannitol

SEX/DURATION :: female 5 day(s) pre-mating female 1-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 27,631,1989

Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	22-26-36/37/39-45
RIDADR	NONH for all modes of transport
RTECS	LZ4394500
HS Code	2940000000

HS Code	2940000000