90906-41-5

90906-41-5 structure

Name: (±)20-HDHA
Chemical Name: 20-hydroxydocosa-4,7,10,13,16,18-hexaenoic acid
CAS Number: 90906-41-5
Molecular Formula: C₂₂H₃₂O₃
Molecular Weight: 344.488
Catalog: Research Areas Neurological Disease
Create Date: 2016-03-26 21:45:11
Modify Date: 2024-01-06 18:05:59
(±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate[1][2][3].

Name	20-hydroxydocosa-4,7,10,13,16,18-hexaenoic acid
Synonyms	4,7,10,13,16,18-Docosahexaenoic acid, 20-hydroxy-, (4Z,7Z,10Z,13Z,16Z,18E)- (4Z,7Z,10Z,13Z,16Z,18E)-20-Hydroxy-4,7,10,13,16,18-docosahexaenoic acid

Description	(±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate[1][2][3].
Related Catalog	Research Areas >> Neurological Disease
In Vitro	Numerous reports demonstrate the beneficial effects of fish oil on human diseases such as arthritis, Alzheimer’s disease, lung fibrosis, and inflammatory bowel diseases. As an essential omega-3 polyunsaturated fatty acid, Docosahexaenoic acid (DHA) is a major component of fish oil[3].
References	[1]. VanRollins M, et al. Autooxidation of docosahexaenoic acid: analysis of ten isomers of hydroxydocosahexaenoate. J Lipid Res. 1984 May;25(5):507-17. [2]. Kim HY, et al. Stereochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenate. Prostaglandins. 1990 Nov;40(5):473-90. [3]. Hong S, et al. Resolvin D1, protectin D1, and related docosahexaenoic acid-derived products: Analysis via electrospray/low energy tandem mass spectrometry based on spectra and fragmentation mechanisms. J Am Soc Mass Spectrom. 2007 Jan;18(1):128-44.