Name | Phthaloyl amlodipine |
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Synonyms |
3-Ethyl 5-methyl 4-(2-chlorophenyl)-2-{[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]methyl}-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate
EINECS 413-410-3 Amlodipine intermediate 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester T56 BVNVJ C2O1- BT6M DHJ CVO2 DR BG& EVO1 F1 3-O-ethyl 5-O-methyl 4-(2-chlorophenyl)-2-[2-(1,3-dioxoisoindol-2-yl)ethoxymethyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate MFCD07782096 Amlodipine Impurity 1 |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 654.1±55.0 °C at 760 mmHg |
Melting Point | 140-145ºC |
Molecular Formula | C28H27ClN2O7 |
Molecular Weight | 538.976 |
Flash Point | 349.4±31.5 °C |
Exact Mass | 538.150696 |
PSA | 111.24000 |
LogP | 6.38 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.589 |
Storage condition | Refrigerator |
~32% 88150-62-3 |
Literature: MATRIX LABORATORIES LTD Patent: WO2006/3672 A1, 2006 ; Location in patent: Page/Page column 6; 7 ; |
~% 88150-62-3 |
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702 |
~% 88150-62-3 |
Literature: Journal of Medicinal Chemistry, , vol. 29, # 9 p. 1696 - 1702 |
~24% 88150-62-3 |
Literature: Arrowsmith; Campbell; Cross; Stubbs; Burges; Gardiner; Blackburn Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1696 - 1702 |
Precursor 6 | |
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DownStream 4 | |