71-62-5

71-62-5 structure

Name: Veratridine
Chemical Name: veratridine
CAS Number: 71-62-5
Molecular Formula: C₃₆H₅₁NO₁₁
Molecular Weight: 673.79000
Catalog: Organic raw materials Carboxylic compounds and derivatives Carboxylic esters and their derivatives
Create Date: 2018-03-05 08:00:00
Modify Date: 2024-01-02 16:26:14
Veratridine (3-Veratroylveracevine), a alkaloid derived from plants in the family Liliaceae, is a sodium channel agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM.

Name	veratridine
Synonyms	Metergoline ,4alpha,16beta) EINECS 200-758-4 Veracevine,veratrate ybenzoate) VERATRIDINE 3-VERATROYLVERACEVINE MFCD00082515

Description	Veratridine (3-Veratroylveracevine), a alkaloid derived from plants in the family Liliaceae, is a sodium channel agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
References	[1]. Zhang XY, et al. Veratridine modifies the gating of human voltage-gated sodium channel Nav1.7. Acta Pharmacol Sin. 2018 Nov;39(11):1716-1724.

WISWESSER LINE NOTATION :: T J6 H6 E6 D5665/TC& 3ATU C& ON TX C&OTJ EQ GQ HQ IQ I1 M1 RQ U1 A&OVR CO1 DO1& B&Q

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 78,238,1943

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 76,847,1951

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,89,1955

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 120,412,1957

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H300 + H310 + H330-H315-H319-H335-H361-H373-H412
Precautionary Statements	P260-P262-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310-P403 + P233
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T+: Very toxic;
Risk Phrases	R26/27/28
Safety Phrases	S26;S36/S37/S39;S45
RIDADR	UN 1544 6
WGK Germany	2
RTECS	YX5600000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2929101000

3535-37-3

71-62-5

Literature: Collection of Czechoslovak Chemical Communications, , vol. 22, p. 98,102

HS Code	2929101000
Summary	2929101000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:6.5%. General tariff:30.0%