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124423-84-3

124423-84-3 structure
124423-84-3 structure
  • Name: panadiplon
  • Chemical Name: 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-propan-2-ylimidazo[1,5-a]quinoxalin-4-one
  • CAS Number: 124423-84-3
  • Molecular Formula: C18H17N5O2
  • Molecular Weight: 335.36
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
  • Create Date: 2018-09-09 15:33:59
  • Modify Date: 2024-01-12 08:07:43
  • Panadiplon (FG 10571; PNU 78875), a benzodiazepine receptor, is a 5GABAA partial agonist. Panadiplon exhibits selectivity for 5GABAA receptors versus 1GABAA receptors[1].

Name 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-propan-2-ylimidazo[1,5-a]quinoxalin-4-one
Synonyms 3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-5-(1-methylethyl)imidazo[1,5-a]quinoxalin-4(5H)-one
Imidazo(1,5-a)quinoxalin-4(5H)-one, 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-(1-methylethyl)-
Imidazo[1,5-a]quinoxalin-4(5H)-one, 3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-(1-methylethyl)-
panadiplon
3-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-5-(propan-2-yl)imidazo[1,5-a]quinoxalin-4(5H)-one
3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-5-isopropylimidazo[1,5-a]quinoxalin-4(5H)-one
Panadiplonum
3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-5-isopropylimidazo(1,5-a)quinoxalin-4(5H)-one
Panadiplone
UNII-V4PW0S7ZP7
Description Panadiplon (FG 10571; PNU 78875), a benzodiazepine receptor, is a 5GABAA partial agonist. Panadiplon exhibits selectivity for 5GABAA receptors versus 1GABAA receptors[1].
Related Catalog
Target

GABA(A)[1]

References

[1]. Platt DM, et al. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. J Pharmacol Exp Ther. 2005 May;313(2):658-67.  

Density 1.5±0.1 g/cm3
Boiling Point 605.4±65.0 °C at 760 mmHg
Molecular Formula C18H17N5O2
Molecular Weight 335.36
Flash Point 319.9±34.3 °C
Exact Mass 335.138214
PSA 78.22000
LogP 1.70
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.785