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  • DC Chemicals Limited
  • China
  • Product Name: 8-Oxo-dG
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

88847-89-6

88847-89-6 structure
88847-89-6 structure

Name 8-hydroxy-2'-deoxyguanosine
Synonyms 2'-deoxy-7,8-dihydro-8-oxo-guanosine
MFCD00210311
2'-Deoxy-8-oxo-7,8-dihydroguanosine
7,8-Dihydro-8-oxo-2'-deoxyguanosine
2'-Deoxy-8-oxoguanosine
8-Oxo-7,8-dihydrodeoxyguanosine
2'-Deoxy-8-oxo-D-guanosine
8-Oxodeoxyguanosine
guanosine, 2'-deoxy-8-oxo-
2'-Deoxy-8-hydroxyguanosine
8-oxo-7,8-dihydro-2'-deoxiguanosine
Guanosine, 2'-deoxy-8-hydroxy-
8-oxo-7-hydrodeoxyguanosine
8-hydroxydeoxyguanosine
8-HYDROXY-2'-DEOXYGUANOSINE
8-Hydroxy-2’-deoxyguanosine
8-oxo-7,8-dihydro-2'-deoxyguanosine
2'-Deoxy-7,8-dihydro-8-oxoguanosine
Description 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons[1].
References

[1]. Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):120-39.

Density 2.3±0.1 g/cm3
Melting Point 217-220ºC
Molecular Formula C10H13N5O5
Molecular Weight 283.241
Exact Mass 283.091675
PSA 159.51000
LogP -1.32
Index of Refraction 1.955
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS MF8782675
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%