Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ZMVR DZ
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Purity: 98.0%
Stocking Period: 10 Day
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DC Chemicals Limited
China
Product Name: Myeloperoxidase Inhibitor 1
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Aminobenzhydrazide
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Purity: 98.0%
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5351-17-7

5351-17-7 structure

5351-17-7 structure

Name: ZMVR DZ
Chemical Name: 4-Aminobenzohydrazide
CAS Number: 5351-17-7
Molecular Formula: C₇H₉N₃O
Molecular Weight: 151.17
Catalog: Chemical reagent Organic reagent 肼
Create Date: 2018-09-20 19:08:47
Modify Date: 2024-01-03 19:30:49
4-Aminobenzohydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 µM[1]. It is used for the research of subacute stroke[2].

Name	4-Aminobenzohydrazide
Synonyms	EINECS 226-324-4 p-Aminobenzoyl Hydrazide 4-aminobenzhydrazide Aminostimil (4-Aminobenzoyl)hydrazide Amben hydrazide p-Aminobenzhydrazide 4-Aminobenzoylhydrazide 4-aminobenzenecarbonylhydrazine 4-Aminobenzoic acid hydrazide 4-Aminobenzohydrazide ZMVR DZ Benzoic acid, 4-amino-, hydrazide 4-Aminobenzoylhydrazine 4-Aminobenzoic hydrazide MFCD00007606 p-Aminobenzoic acid hydrazide

Description	4-Aminobenzohydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 µM[1]. It is used for the research of subacute stroke[2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Kettle AJ, et al. Inhibition of myeloperoxidase by benzoic acid hydrazides. Biochem J. 1995 Jun 1;308 ( Pt 2)(Pt 2):559-63. [2]. Forghani R, et al. Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke. J Cereb Blood Flow Metab. 2015 Mar;35(3):485-93.

Density	1.3±0.1 g/cm3
Melting Point	225-227 °C(lit.)
Molecular Formula	C₇H₉N₃O
Molecular Weight	151.17
Exact Mass	151.074554
PSA	81.14000
LogP	-0.75
Index of Refraction	1.641

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG2580000

CHEMICAL NAME :: Benzoic acid, p-amino-, hydrazide

CAS REGISTRY NUMBER :: 5351-17-7

BEILSTEIN REFERENCE NO. :: 0639053

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H9-N3-O

MOLECULAR WEIGHT :: 151.19

WISWESSER LINE NOTATION :: ZNUYQR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01358

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DG2580000
HS Code	2928000090

Precursor 10
619-45-4 94-09-7 150-13-0 99-77-4
636-97-5 4005-02-1 10073-94-6 619-50-1
16106-38-0 62-23-7
DownStream 10
14070-13-4 35219-13-7 32058-82-5 2425-95-8
556-18-3 127786-22-5 127786-20-3 127786-18-9
127786-25-8 127786-24-7

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%