38873-55-1

38873-55-1 structure

Name: Furobufen
Chemical Name: 4-dibenzofuran-2-yl-4-oxobutanoic acid
CAS Number: 38873-55-1
Molecular Formula: C₁₆H₁₂O₄
Molecular Weight: 268.26400
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-02-11 08:00:00
Modify Date: 2024-01-12 22:13:12
Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue[1].

Name	4-dibenzofuran-2-yl-4-oxobutanoic acid
Synonyms	4-dibenzofuran-2-yl-4-oxo-butyric acid Furobufenum [INN-Latin] Furobufene [French] Furobufeno [INN-Spanish] Furobufen Furobufeno [Spanish] 4-Dibenzofuran-2-yl-4-oxo-buttersaeure Furobufene [INN-French]

Description	Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
In Vivo	Furobufen (po; 10, 30, 90 mg/kg; once daily; 7 days) produces a dose-related inhibition of the paw edema produced by carrageenan in male rats weighing 180-200 g[1].
References	[1]. Martel RR, et al. Anti-inflammatory properties of furobufen. Can J Physiol Pharmacol. 1974 Jun;52(3):669-73.

Density	1.343g/cm3
Boiling Point	509.8ºC at 760 mmHg
Molecular Formula	C₁₆H₁₂O₄
Molecular Weight	268.26400
Flash Point	262.1ºC
Exact Mass	268.07400
PSA	67.51000
LogP	3.63350
Index of Refraction	1.676

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HP4930000

CHEMICAL NAME :: 2-Dibenzofuranbutanoic acid, gamma-oxo-

CAS REGISTRY NUMBER :: 38873-55-1

BEILSTEIN REFERENCE NO. :: 0250326

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H12-O4

MOLECULAR WEIGHT :: 268.28

WISWESSER LINE NOTATION :: T B656 HOJ DV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1283 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CJPPA3 Canadian Journal of Physiology and Pharmacology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.42- 1964- Volume(issue)/page/year: 52,669,1974

HS Code	2932999099

108-30-5

132-64-9

38873-55-1

Literature: Mayer; Krieger Chemische Berichte, 1922 , vol. 55, p. 1664 Full Text Show Details Hoechster Farbw. Patent: DE376635 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 285 Full Text Show Details Krieger Diss. , S. 6, 14, 37

36109-81-6

38873-55-1

Literature: American Home Products Corporation Patent: US3985774 A1, 1976 ;

Precursor 3
108-30-5 132-64-9 36109-81-6
DownStream 0

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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