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701-54-2

701-54-2 structure
701-54-2 structure

Name Tranexamic acid
Synonyms 1-(biphenyl-4-yl)methanamine
4-aminomethylcyclohexane-1-carboxylic acid
(4-phenylphenyl)methylamine
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-aminomethylbiphenyl
4-Aminomethyl-cyclohexancarbonsaeure
4-Aminomethyl-cyclohexanecarboxylic acid
4-Biphenylmethylamine
4-(Aminomethyl)cyclohexanecarboxylic acid
[1,1'-biphenyl]-4-yl methanamine
C-biphenyl-4-yl-methylamine
4-aminomethylcyclohexane carboxylic acid
4-carboxycyclohexylmethylamine
MFCD00064951
Cyclohexanecarboxylic acid, 4-(aminomethyl)-
(biphenyl-4-ylmethyl)amine
4-Phenylbenzylamine
Density 1.1±0.1 g/cm3
Boiling Point 300.2±15.0 °C at 760 mmHg
Melting Point 233ºC
Molecular Formula C8H15NO2
Molecular Weight 157.210
Flash Point 135.4±20.4 °C
Exact Mass 157.110275
PSA 63.32000
LogP 0.31
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.497
Storage condition Refrigerator

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU8399950
CHEMICAL NAME :
Cyclohexanecarboxylic acid, 4-(aminomethyl)-
CAS REGISTRY NUMBER :
701-54-2
LAST UPDATED :
199509
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C8-H15-N-O2
MOLECULAR WEIGHT :
157.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32500 mg/kg/13W-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
RTECS GU8399950
HS Code 2922499990
HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%