Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,4-dimethoxy-N-(4-(3-nitrophenyl)-5-(piperidin-1-ylmethyl)thiazol-2-yl)benzenesulfonamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1008119-83-2

1008119-83-2 structure

Name: JM6
Chemical Name: 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-1,3-th iazol-2-yl]benzenesulfonamide
CAS Number: 1008119-83-2
Molecular Formula: C₂₃H₂₆N₄O₆S₂
Molecular Weight: 518.60600
Catalog: Research Areas Neurological Disease
Create Date: 2018-12-28 15:54:58
Modify Date: 2024-01-04 14:12:37
JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC50 of 19.85 μM for mouse KMO. JM6 can be used for Alzheimer's diseases research[1].

Name	3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-1,3-th iazol-2-yl]benzenesulfonamide
Synonyms	3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide JM6

Description	JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC50 of 19.85 μM for mouse KMO. JM6 can be used for Alzheimer's diseases research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	IC50: 19.85 μM (kynurenine 3-monooxygenase)[1]
References	[1]. Maria G Beconi, et al. Metabolism and pharmacokinetics of JM6 in mice: JM6 is not a prodrug for Ro-61-8048. Drug Metab Dispos. 2012 Dec;40(12):2297-306.