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934662-91-6

934662-91-6 structure
934662-91-6 structure
  • Name: Cobimetinib (racemate)
  • Chemical Name: [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone
  • CAS Number: 934662-91-6
  • Molecular Formula: C21H21F3IN3O2
  • Molecular Weight: 531.31000
  • Catalog: Research Areas Cancer
  • Create Date: 2016-04-01 06:23:48
  • Modify Date: 2024-01-02 17:30:57
  • Cobimetinib racemate is the less active racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor.

Name [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone
Synonyms GDC0973
GDC-0973 racemate
GDC-0973 racemate||GDC 0973|XL 518|GDC0973|XL518
CS-1043
Cobimetinib (racemate)
Description Cobimetinib racemate is the less active racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor.
Related Catalog
References

[1]. Hoeflich KP, et al. Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition. Cancer Res. 2012 Jan 1;72(1):210-9.

Molecular Formula C21H21F3IN3O2
Molecular Weight 531.31000
Exact Mass 531.06300
PSA 64.60000
LogP 4.12080
Storage condition 2-8℃