28845-86-5

28845-86-5 structure

Name: Docosatrienoic acid
Chemical Name: (13Z,16Z,19Z)-docosatrienoic acid
CAS Number: 28845-86-5
Molecular Formula: C₂₂H₃₈O₂
Molecular Weight: 334.536
Catalog: Natural Products Others
Create Date: 2019-01-02 19:04:14
Modify Date: 2024-01-09 14:15:43
Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.

Name	(13Z,16Z,19Z)-docosatrienoic acid
Synonyms	13,16,19-Docosatrienoic acid, (13E,16E,19E)- 13Z,16Z,19Z-DOCOSATRIENOIC ACID Cis,cis,cis 13C,16C,19C-DOCOSATRIENOIC ACID CIS-13,16,19-DOCOSATRIENOIC ACID Cis,cis,cis-13,16,19-Docosatrienoic Docosa-13Z,16Z,19Z-trienoic acid,22:3,N-3 (13E,16E,19E)-13,16,19-Docosatrienoic acid 13-cis,16-cis,19-cis-Docosatrienoic acid DOCOSATRIENOIC ACID DOCOSA-13Z,16Z,19Z-TRIENOIC ACID

Description	Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.
Related Catalog	Research Areas >> Cardiovascular Disease Natural Products >> Others
Target	Human Endogenous Metabolite
In Vitro	Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM[1].
In Vivo	Application of docosatrienic acid dose-dependently decreases the peak K+ current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials[2].
References	[1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7. [2]. Krutetskaia ZI, et al. The effect of docosatrienoic acid on the potassium channels of outward rectification in the membrane of rat peritoneal macrophages. Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):111-9.