Name | 1,3-dicyclohexylurea |
---|---|
Synonyms |
F0902-7614
MFCD00003829 Methanol, 1-(cyclohexylamino)-1-(cyclohexylimino)-, (E)- EINECS 219-213-7 N,N'-Dicyclohexylurea 1,3-Dicyclohexylurea N,N-Dicyclohexylurea Urea, N,N'-dicyclohexyl- Urea,3-dicyclohexyl dicyclohexyl urea N,N‘-Dicyclohexylurea 1,3-dicyclohexyl-urea N,N'-Dicyclohexylcarbamimidic acid DCW N,N′-Dicyclohexylurea Urea,N'-dicyclohexyl 1,3-dicyclohexylcarbodiimide Urea,N,N'-dicyclohexyl |
Description | 1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1]. |
---|---|
Related Catalog | |
In Vivo | 1,3-Dicyclohexylurea (Sprague Dawley rats, 30 mg/kg, Orally, once) shows antihypertensive efficacy when milled to reduce particle size, thus improving dissolution and oral bioavailability[1]. |
References |
Density | 1.2±0.1 g/cm3 |
---|---|
Boiling Point | 364.3±25.0 °C at 760 mmHg |
Melting Point | 232-233 °C(lit.) |
Molecular Formula | C13H24N2O |
Molecular Weight | 224.34 |
Flash Point | 174.1±23.2 °C |
Exact Mass | 224.188858 |
PSA | 41.13000 |
LogP | 3.85 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.586 |
Symbol |
GHS07 |
---|---|
Signal Word | Warning |
Hazard Statements | H302 |
Precautionary Statements | P301 + P312 + P330 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn: Harmful;N: Dangerous for the environment; |
Risk Phrases | 22-51/53 |
Safety Phrases | S61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | 3 |
HS Code | 2924299090 |
Precursor 10 | |
---|---|
DownStream 10 | |
HS Code | 2924299090 |
---|---|
Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |