89595-66-4

89595-66-4 structure

Name: Prunetin 5-O-β-D-glucopyranoside
Chemical Name: 5,4'-dihydroxy-7-methoxyisoflavone-4'-o-glucoside
CAS Number: 89595-66-4
Molecular Formula: C₂₂H₂₂O₁₀
Molecular Weight: 446.40400
Catalog: Research Areas Metabolic Disease
Create Date: 2017-04-04 21:40:32
Modify Date: 2024-01-08 22:47:28
Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes[1].

Name	5,4'-dihydroxy-7-methoxyisoflavone-4'-o-glucoside
Synonyms	prunetin-4'-glucoside prunitrin

Description	Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	IC50: 56.05 μg/mL (α-glucosidase)[1]
References	[1]. Şöhretoğlu D, et, al. α-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies. Int J Biol Macromol. 2017 Dec; 105(Pt 1):1062-1070.

Precursor 0
DownStream 1
552-59-0