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219138-08-6

219138-08-6 structure
219138-08-6 structure
  • Name: Z-Val-Asp-Val-Ala-Asp-AFC
  • Chemical Name: z-vdvad-afc
  • CAS Number: 219138-08-6
  • Molecular Formula: C39H45F3N6O13
  • Molecular Weight: 862.80
  • Catalog: Biochemical Amino acids and their derivatives Aspartic acid derivative
  • Create Date: 2018-12-25 16:42:23
  • Modify Date: 2024-04-05 14:20:43
  • Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].

Name z-vdvad-afc
Synonyms Z-Val-Asp-Ala-Asp-AFC
PASE-2 SUBSTRATE I,FLUOROGENIC
Z-VAL-ASP-VAL-ALA-ASP-AFC
Description Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1].
Related Catalog
References

[1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79.  

Molecular Formula C39H45F3N6O13
Molecular Weight 862.80
Exact Mass 862.30000
PSA 288.64000
LogP 4.29330
Storage condition -15°C