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40252-74-2

40252-74-2 structure
40252-74-2 structure
  • Name: DMeOB
  • Chemical Name: (E)-1-(3-methoxyphenyl)-N-[(E)-(3-methoxyphenyl)methylideneamino]methanimine
  • CAS Number: 40252-74-2
  • Molecular Formula: C16H16N2O2
  • Molecular Weight: 268.31
  • Catalog: Signaling Pathways GPCR/G Protein mGluR
  • Create Date: 2017-01-21 08:11:17
  • Modify Date: 2024-01-10 08:33:29
  • DMeOB is an agonist of mGluR5 receptor with an IC50 of 3 μM. DMeOB has a negative modulatory effect[1].

Name (E)-1-(3-methoxyphenyl)-N-[(E)-(3-methoxyphenyl)methylideneamino]methanimine
Synonyms 3,3'-dimethoxybenzalazine
DMeOB
m-anisaldehyde azine
3,3'-dimethoxybenzaldazine
3-Methoxybenzaldehyde [(3-methoxyphenyl)methylene]hydrazone
3-methoxybenzaldehyde azine
Description DMeOB is an agonist of mGluR5 receptor with an IC50 of 3 μM. DMeOB has a negative modulatory effect[1].
Related Catalog
References

[1]. O'Brien JA, et al. A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5. Mol Pharmacol. 2003 Sep;64(3):731-40.  

Density 1.05g/cm3
Boiling Point 438.2ºC at 760mmHg
Molecular Formula C16H16N2O2
Molecular Weight 268.31
Flash Point 176.1ºC
Exact Mass 268.12100
PSA 43.18000
LogP 3.15680
Index of Refraction 1.54
Storage condition 2-8°C
Symbol GHS05 GHS09
GHS05, GHS09
Signal Word Danger
Hazard Statements H318-H400
Precautionary Statements P273-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;N: Dangerous for the environment;
Risk Phrases 41-50/53
Safety Phrases 26-36/37/39-60-61
RIDADR UN 3077 9/PG 3

~80%

40252-74-2 structure

40252-74-2

Literature: O'Brien, Julie A.; Lemaire, Wei; Chen, Tsing-Bau; Chang, Raymond S. L.; Jacobson, Marlene A.; Ha, Sookhee N.; Lindsley, Craig W.; Schaffhauser, Herve J.; Sur, Cyrille; Pettibone, Douglas J.; Conn, P. Jeffrey; Williams Jr., David L. Molecular Pharmacology, 2003 , vol. 64, # 3 p. 731 - 740

~%

40252-74-2 structure

40252-74-2

Literature: Pietra; Trinchera Gazzetta Chimica Italiana, 1956 , vol. 86, p. 1045,1050

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40252-74-2 structure

40252-74-2

Detail
Literature: Tomioka, Hideo; Tabayashi, Kazuo; Ozaki, Yasuji; Izawa, Yasuji Tetrahedron, 1985 , vol. 41, # 8 p. 1435 - 1440