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50-19-1

50-19-1 structure
50-19-1 structure
  • Name: Oxyfenamate
  • Chemical Name: (2-hydroxy-2-phenylbutyl) carbamate
  • CAS Number: 50-19-1
  • Molecular Formula: C11H15NO3
  • Molecular Weight: 209.24200
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-02-26 08:00:00
  • Modify Date: 2024-01-08 11:46:57
  • Oxyfenamate has anti-anxiety actions for use in anxiety neuroses.

Name (2-hydroxy-2-phenylbutyl) carbamate
Synonyms 2-Hydroxy-2-phenylbutyl-carbamat
Phenylbutamate
Hydroxyphenamate
Listica
Oxifenamatum
oxyfenamate
Hidroxifenamato
Tensifen
AL-0361
Oxyphenamate
Oxifenamate
Hydroxyphenamat
Description Oxyfenamate has anti-anxiety actions for use in anxiety neuroses.
Related Catalog
Density 1.18g/cm3
Boiling Point 415.4ºC at 760 mmHg
Molecular Formula C11H15NO3
Molecular Weight 209.24200
Flash Point 205.1ºC
Exact Mass 209.10500
PSA 72.55000
LogP 2.07980
Index of Refraction 1.545
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK2450000
CHEMICAL NAME :
1,2-Butanediol, 2-phenyl-, 1-carbamate
CAS REGISTRY NUMBER :
50-19-1
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C11-H15-N-O3
MOLECULAR WEIGHT :
209.27
WISWESSER LINE NOTATION :
ZVO1XQ2&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
607 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,394,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
830 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
425 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
233 gm/kg/52W-I
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Related to Chronic Data - death
REFERENCE :
DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961
HS Code 2924299090
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%