56592-32-6

56592-32-6 structure

Name: efrotomycin
Chemical Name: 2-[2,3-dihydroxy-4-[3-hydroxy-5-(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)oxy-4-methoxy-6-methyloxan-2-yl]oxy-5,5-dimethyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-N-[(2E,4E)-7-[3,4-dihydroxy-5-[(1E,3E,5E,7E)-7-hydroxy-6-methyl-7-(1-methyl-2,4-dioxopyridin
CAS Number: 56592-32-6
Molecular Formula: C₅₉H₈₈N₂O₂₀
Molecular Weight: 1145.33000
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-03-04 08:00:00
Modify Date: 2024-01-11 22:02:42
Efrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs[1][2].

Name	2-[2,3-dihydroxy-4-[3-hydroxy-5-(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)oxy-4-methoxy-6-methyloxan-2-yl]oxy-5,5-dimethyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-N-[(2E,4E)-7-[3,4-dihydroxy-5-[(1E,3E,5E,7E)-7-hydroxy-6-methyl-7-(1-methyl-2,4-dioxopyridin
Synonyms	Antibiotic FR 02A Producil FR 02A efrotomycin MK-621

Description	Efrotomycin is an orally active antibiotic. Efrotomycin can be isolated from the Streptomyces Lactamdurans. Efrotomycin has insignificant effect on Salmonella typhimurium quantity, duration, shedding rate, and antimicrobial susceptibility in infected pigs[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vivo	Efrotomycin (16 mg/kg; 口服，加在饲料中; 共 56 天) 处理鼠伤寒沙门菌感染的猪，不影响脱落的菌落在定植后对抗菌药物的敏感性[1]。 Efrotomycin (16 mg/kg; 口服; 共 56 天) 处理的猪，在饲料消耗、体重增加或饲料效率方面没有明显差异[1]。
References	[1]. Wax R, et al. Efrotomycin, a new antibiotic from Streptomyces lactamdurans. J Antibiot (Tokyo). 1976 Jun;29(6):670-3. [2]. Jacks TM, et al. Effect of efrotomycin in feed on the quantity, duration, and prevalence of shedding and antibacterial susceptibility of Salmonella typhimurium in experimentally infected swine. Am J Vet Res. 1988 Nov;49(11):1832-5.