Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Norepinephrine
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Purity: 95.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: DL-Noradrenaline
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: DL-NORADRENALINE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
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138-65-8

138-65-8 structure

138-65-8 structure

Name: Norepinephrine
Chemical Name: noradrenaline
CAS Number: 138-65-8
Molecular Formula: C₈H₁₁NO₃
Molecular Weight: 169.178
Create Date: 2018-02-13 08:00:00
Modify Date: 2024-01-03 14:51:19

Name	noradrenaline
Synonyms	1-(3,4-Dihydroxy)phenyl-2-aminoethanol (-)-NORADRENALINE 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-(-)- 4-[(1R)-2-amino-1-hydroxyéthyl]benzène-1,2-diol L-NOREPINEPHRINE (+)-Norepinephrin 4-((R)-2-Amino-1-hydroxy-ethyl)-benzene-1,2-diol 1,2-Benzenediol, 4-[(1R)-2-amino-1-hydroxyethyl]- (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol EINECS 205-337-9 4-(1-Hydroxy-2-aminoethyl)catechol R-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol norepinephrinum [INN_la] noradrenaline DL-ARTERENOL 1,2-Benzenediol, 4-((R)-2-amino-1-hydroxyethyl)- [3H]-(+/-)-Norepinephrine 3,4-Dhydroxyphenylethanolamine L-NORADRENALINE (R)-(-)-norepinephrine DL-NOREPINEPHRINE (+/-)-Norepinephrine (-)-a-(Aminomethyl)protocatechuyl alcohol 4-[(1R)-2-Amino-1-hydroxyethyl]benzol-1,2-diol Noradrenalin [14C]-(+/-)-Norepinephrine (-)-norepinephrine (R)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol (R)-norepinephrine Racemic norepinephrine (R)-noradrenaline 4-[(1R)-2-Amino-1-hydroxyethyl]benzene-1,2-diol MFCD00066505 (-)-(R)-Norepinephrine 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)- DL-Noradrenaline 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol 4-[(1RS)-2-amino-1-hydroxyethyl]-1,2-benzenediol

Density	1.4±0.1 g/cm3
Boiling Point	442.6±40.0 °C at 760 mmHg
Melting Point	-190ºC (dec.)
Molecular Formula	C₈H₁₁NO₃
Molecular Weight	169.178
Flash Point	221.5±27.3 °C
Exact Mass	169.073898
PSA	86.71000
LogP	-0.88
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.659

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DN6300000

CHEMICAL NAME :: Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (+-)-

CAS REGISTRY NUMBER :: 138-65-8

LAST UPDATED :: 199106

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H11-N-O3

MOLECULAR WEIGHT :: 169.20

WISWESSER LINE NOTATION :: Z1YQR CQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 68,501,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 130 ug/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 95,502,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15600 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 68,501,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,64,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4700 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 95,502,1949

Hazard Codes	T+: Very toxic;
Risk Phrases	R28
Safety Phrases	S28;S45;S36/S37/S39
WGK Germany	3
RTECS	DN6300000
HS Code	2922509090

Precursor 9
104819-57-0 5090-29-9 409109-83-7 51-61-6
67632-28-4 72712-21-1 120-80-9 645-36-3
499-61-6
DownStream 9
14309-96-7 50-53-3 149-95-1 51-41-2
15069-79-1 3569-19-5 490-89-1 5707-55-1
3770-01-2

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%