Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2-Propanediol,3-(2-methylphenoxy)-, 1-carbamate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

533-06-2

533-06-2 structure

533-06-2 structure

Name: 1,2-Propanediol,3-(2-methylphenoxy)-, 1-carbamate
Chemical Name: [2-hydroxy-3-(2-methylphenoxy)propyl] carbamate
CAS Number: 533-06-2
Molecular Formula: C₁₁H₁₅NO₄
Molecular Weight: 225.24100
Create Date: 2017-08-30 06:58:38
Modify Date: 2024-03-14 18:19:54

Name	[2-hydroxy-3-(2-methylphenoxy)propyl] carbamate
Synonyms	2-hydroxy-3-(o-tolyloxy)propyl carbamate 2-Carbamoyloxy-3-o-tolyloxy-propan-1-ol carbamic acid-(2-hydroxy-3-o-tolyloxy-propyl ester) Mephenesin carbamate 1,2-Propanediol,3-(o-tolyloxy)-,1-carbamate 3-o-Toloxy-2-hydroxypropyl 1-carbamate Tolseram 1-Hydrazinocarbonyloxy-3-(o-methylphenoxy)-2-propanol Kimavoxyl 3-(o-Methylphenoxy)-1,2-propandiol-1-carbamat Carbamidsaeure-(2-hydroxy-3-o-tolyloxy-propylester) 3-o-Tolyloxy-2-hydroxypropyl 1-carbamate 2-Hydroxy-3-o-tolyloxypropyl 1-carbamate SQ 2303

Density	1.222g/cm3
Boiling Point	461.4ºC at 760mmHg
Molecular Formula	C₁₁H₁₅NO₄
Molecular Weight	225.24100
Flash Point	232.8ºC
Exact Mass	225.10000
PSA	81.78000
LogP	1.53030
Index of Refraction	1.547

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FB2710000

CHEMICAL NAME :: Carbamic acid, 2-hydroxy-3-(o-tolyloxy)propyl ester

CAS REGISTRY NUMBER :: 533-06-2

BEILSTEIN REFERENCE NO. :: 1880597

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C11-H15-N-O4

MOLECULAR WEIGHT :: 225.27

WISWESSER LINE NOTATION :: ZVO1YQ1OR B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1050 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 413 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1050 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 490 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 982 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 385 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle weakness Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 129,75,1960

HS Code	2924299090

4549-72-8 structure

4549-72-8

~%

533-06-2 structure

533-06-2

Literature: Yale et al. Journal of the American Chemical Society, 1950 , vol. 72, p. 3716

75-44-5 structure

75-44-5

59-47-2 structure

59-47-2

~%

533-06-2 structure

533-06-2

Literature: Yale et al. Journal of the American Chemical Society, 1950 , vol. 72, p. 3716

Precursor 3
4549-72-8 75-44-5 59-47-2
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%