219649-95-3

219649-95-3 structure

Name: Griffipavixanthone
Chemical Name: (8S,8aS,12aR)-1,3,6,7-Tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-te trahydroxy-9-oxo-9H-xanthen-1-yl)-8a,9,10,12a-tetrahydroindeno[1, 2-a]xanthen-13(8H)-one
CAS Number: 219649-95-3
Molecular Formula: C₃₆H₂₈O₁₂
Molecular Weight: 652.60
Catalog: Natural product Xanthone
Create Date: 2016-05-11 10:01:06
Modify Date: 2024-01-10 19:25:40
Griffipavixanthone can be extracted from Garcinia schomburgkiana. Griffipavixanthone induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. Griffipavixanthone is an anti-cancer agent. Griffipavixanthone is a weak sucrase inhibitor (IC50: 4.58 mM)[1][2][3].

Name	(8S,8aS,12aR)-1,3,6,7-Tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-te trahydroxy-9-oxo-9H-xanthen-1-yl)-8a,9,10,12a-tetrahydroindeno[1, 2-a]xanthen-13(8H)-one
Synonyms	(8S,8aS,12aR)-1,3,6,7-Tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxo-9H-xanthen-1-yl)-8a,9,10,12a-tetrahydroindeno[1,2-a]xanthen-13(8H)-one Indeno[1,2-a]xanthen-13(8H)-one, 8a,9,10,12a-tetrahydro-1,3,6,7-tetrahydroxy-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxo-9H-xanthen-1-yl)-, (8S,8aS,12aR)-

Description	Griffipavixanthone can be extracted from Garcinia schomburgkiana. Griffipavixanthone induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. Griffipavixanthone is an anti-cancer agent. Griffipavixanthone is a weak sucrase inhibitor (IC50: 4.58 mM)[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Lien Do TM, et al. Schomburgkixanthone, a novel bixanthone from the twigs of Garcinia schomburgkiana. Nat Prod Res. 2021 Nov;35(21):3613-3618. [2]. Shi JM, et al. Griffipavixanthone from Garcinia oblongifolia champ induces cell apoptosis in human non-small-cell lung cancer H520 cells in vitro. Molecules. 2014 Jan 27;19(2):1422-31. [3]. Ma Y, et al. Griffipavixanthone induces apoptosis of human breast cancer MCF-7 cells in vitro. Breast Cancer. 2019 Mar;26(2):190-197.

Hazard Codes	Xi