56821-03-5

56821-03-5 structure

56821-03-5 structure

Name: 2-Chlorophenoxazine
Chemical Name: 2-chloro-10H-phenoxazine
CAS Number: 56821-03-5
Molecular Formula: C₁₂H₈ClNO
Molecular Weight: 217.65
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2016-05-29 05:38:41
Modify Date: 2023-01-14 18:23:48
2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis.2-Chlorophenoxazine can be used for cancer diseases research[1].

Name	2-chloro-10H-phenoxazine
Synonyms	2-chlorophenoxazine 10H-Phenoxazine,2-chloro 2-chlorphenoxazine

Description	2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis.2-Chlorophenoxazine can be used for cancer diseases research[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Thimmaiah KN, et al. Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35

Molecular Formula	C₁₂H₈ClNO
Molecular Weight	217.65
Exact Mass	217.02900
PSA	21.26000
LogP	4.32730

60344-80-1 structure

60344-80-1

~75%

56821-03-5 structure

56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259

95-56-7 structure

95-56-7

~%

56821-03-5 structure

56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259

105837-78-3 structure

105837-78-3

~%

56821-03-5 structure

56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259

105790-01-0 structure

105790-01-0

~%

56821-03-5 structure

56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259

89-61-2 structure

89-61-2

~%

56821-03-5 structure

56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259

320785-96-4 structure

320785-96-4

~%

56821-03-5 structure

56821-03-5

Literature: Eregowda; Kalpana; Hegde; Thimmaiah Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 4 p. 243 - 259

108953-08-8 structure

108953-08-8

~%

56821-03-5 structure

56821-03-5

Literature: Cieslak,J. et al. Roczniki Chemii, 1960 , vol. 34, p. 103 - 110

Precursor 6
95-56-7 105837-78-3 105790-01-0 89-61-2
320785-96-4 108953-08-8
DownStream 0