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77279-24-4

77279-24-4 structure
77279-24-4 structure
  • Name: 1-BOC-4-(2-hydroxyethyl)piperazine
  • Chemical Name: Tert-Butyl 4-(2-Hydroxyethyl)Piperazine-1-Carboxylate
  • CAS Number: 77279-24-4
  • Molecular Formula: C11H22N2O3
  • Molecular Weight: 230.304
  • Create Date: 2018-12-02 20:19:23
  • Modify Date: 2024-01-08 11:15:48

Name Tert-Butyl 4-(2-Hydroxyethyl)Piperazine-1-Carboxylate
Synonyms 1-Piperazinecarboxylic acid, 4-(2-hydroxyethyl)-, 1,1-dimethylethyl ester
1-BOC-4-(2-hydroxyethyl)piperazine
4-(2-Hydroxyethyl)-1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
Tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate
2-Methyl-2-propanyl 4-(2-hydroxyethyl)-1-piperazinecarboxylate
MFCD00728947
Density 1.1±0.1 g/cm3
Boiling Point 333.6±32.0 °C at 760 mmHg
Melting Point 39ºC
Molecular Formula C11H22N2O3
Molecular Weight 230.304
Flash Point 155.5±25.1 °C
Exact Mass 230.163040
PSA 53.01000
LogP 0.68
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.493
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H400
Precautionary Statements P273-P301 + P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes C: Corrosive;N: Dangerous for the environment;T: Toxic;
Risk Phrases R25;R50
Safety Phrases 26-36/37/39
RIDADR UN 2811
HS Code 2933599090

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77279-24-4 structure

77279-24-4

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2006/107923 A1, 2006 ; Location in patent: Page/Page column 66 ;

~86%

77279-24-4 structure

77279-24-4

Literature: Hoffmann-La Roche Inc.; Hermann, Johannes Cornelius; Kuglstatter, Andreas; Lucas, Matthew C.; Padilla, Fernando; Wanner, Jutta; Zhang, Xiaohu Patent: US2013/109661 A1, 2013 ; Location in patent: Paragraph 0620-0621 ;

~87%

77279-24-4 structure

77279-24-4

Literature: Hill, Pamela J.; Abibi, Ayome; Albert, Robert; Andrews, Beth; Gagnon, Moriah M.; Gao, Ning; Grebe, Tyler; Hajec, Laurel I.; Huang, Jian; Livchak, Stephania; Lahiri, Sushmita D.; McKinney, David C.; Thresher, Jason; Wang, Hongming; Olivier, Nelson; Buurman, Ed T. Journal of Medicinal Chemistry, 2013 , vol. 56, # 18 p. 7278 - 7288

~85%

77279-24-4 structure

77279-24-4

Literature: Honda, Toshio; Ishikawa, Fumihiro Synthetic Communications, 1999 , vol. 29, # 19 p. 3323 - 3328

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77279-24-4 structure

77279-24-4

Literature: Bulletin of the Korean Chemical Society, , vol. 33, # 5 p. 1547 - 1550

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77279-24-4 structure

77279-24-4

Literature: Bulletin of the Korean Chemical Society, , vol. 33, # 9 p. 2971 - 2975

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77279-24-4 structure

77279-24-4

Literature: Bulletin of the Korean Chemical Society, , vol. 33, # 9 p. 2971 - 2975
HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%