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2897-21-4

2897-21-4 structure
2897-21-4 structure
  • Name: Seleno-DL-cystine
  • Chemical Name: (R,R)-3,3'-diselenobis-(2-aminopropionic acid)
  • CAS Number: 2897-21-4
  • Molecular Formula: C6H12N2O4Se2
  • Molecular Weight: 334.09
  • Catalog: Research Areas Cancer
  • Create Date: 2018-03-13 08:00:00
  • Modify Date: 2024-01-06 15:12:06
  • Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].

Name (R,R)-3,3'-diselenobis-(2-aminopropionic acid)
Synonyms seleno-dl-cystine
alanine,3,3'-diselenobis-
Description Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].
Related Catalog
Target

IC50: Anti-cancer[1]

References

[1]. Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046.  

Molecular Formula C6H12N2O4Se2
Molecular Weight 334.09
Exact Mass 335.91300
PSA 126.64000
Vapour Pressure 5.12E-13mmHg at 25°C
Storage condition -20°C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301 + H331-H373-H410
Precautionary Statements P261-P273-P301 + P310-P311-P501
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T+
Risk Phrases 23/25-33-50/53
Safety Phrases 20/21-28-45-60-61
RIDADR UN 2811 6.1/PG 3
WGK Germany 3.0
RTECS AY6031000
HS Code 2922499990
HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%