66504-75-4
66504-75-4 structure
- Name: Bicifadine hydrochloride
- Chemical Name: Bicifadine Hydrochloride
- CAS Number: 66504-75-4
- Molecular Formula: C12H15N
- Molecular Weight: 173.25400
- Create Date: 2018-12-28 15:00:02
- Modify Date: 2024-04-11 18:33:16
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Bicifadine HCl, also known as DOV-220075, CL 220,075, is a SNDR inhibitor potentially for the treatment of lower back pain. Bicifadine has a non-opioid, non-NSAID mechanism for the treatment of pain, which should have less abuse potential than opioid drugs and less propensity to cause gastric ulcers than NSAID drugs. While the drug is purported to be a serotonin (SERT) and noradrenaline transporter (NET) inhibitor, it also has effects at the dopamine transporter (DAT), effectively making it a broad-spectrum monoamine transporter inhibitor or "triple reuptake inhibitor."
| Name | Bicifadine Hydrochloride |
|---|---|
| Synonyms | bicifadine |
| Molecular Formula | C12H15N |
|---|---|
| Molecular Weight | 173.25400 |
| Exact Mass | 173.12000 |
| PSA | 12.03000 |
| LogP | 2.18470 |
| HS Code | 2933990090 |
|---|
| Precursor 3 | |
|---|---|
| DownStream 1 | |
![3-Azabicyclo[3.1.0]hexane-2,4-dione, 1-(4-methylphenyl)- structure](https://image.chemsrc.com/caspic/498/66504-87-8.png)
![(-)-1-(p-Chlorophenyl)-3-azabicyclo[3.1.0]hexane hydrochloride structure](https://image.chemsrc.com/caspic/034/66503-82-0.png)
![3-methyl-1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane,hydrochloride structure](https://image.chemsrc.com/caspic/412/66504-89-0.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |