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88898-17-3

88898-17-3 structure
88898-17-3 structure
  • Name: Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) trifluoroacetate salt
  • Chemical Name: Atrial natriuretic factor (1-28) (rat)
  • CAS Number: 88898-17-3
  • Molecular Formula: C128H205N45O39S2
  • Molecular Weight: 3062.41000
  • Catalog: Peptides
  • Create Date: 2018-06-19 17:45:05
  • Modify Date: 2024-01-02 20:39:08
  • Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.

Name Atrial natriuretic factor (1-28) (rat)
Synonyms ranf
ranp
cardionatrin
MFCD00076228
anp 1-28,rat
anf 1-28
SLRRSSCFGGRIDRIGAQSGLGCNSFRY(Disulfidebridge:7-23)
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR: SLRRSSCFGGRIDRIGAQSGLGCNSFRY DISULFIDE BRIDGE CYS7-CYS23
SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG(DISULFIDE BRIDGE:CYS3-CYS18)
ANF (1-28),RAT
α-Atriopeptin
SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR(DISULFIDE BRIDGE:CYS7-CYS23)
Atrial Natriuretic Peptide (ANP) (1-28), rat
Description Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner.
Related Catalog
Target

Endothelin-1[1]

In Vitro Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1].
References

[1]. Kohno M, et al. Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kidney Int. 1992 Oct;42(4):860-6.

Molecular Formula C128H205N45O39S2
Molecular Weight 3062.41000
Exact Mass 3060.49000
PSA 1453.98000
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport