Name | Carbocalcitonin |
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Synonyms |
N-{[(2S,5S,8S,11S,14S,17S)-5-(2-Amino-2-oxoethyl)-14-[(1R)-1-hydroxyethyl]-2,11-bis(hydroxymethyl)-8-isobutyl-3,6,9,12,15,23-hexaoxo-1,4,7,10,13,16-hexaazacyclotricosan-17-yl]carbonyl}-L-valyl-L-leucy ;lglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-α-aspartyl-L-valylglycyl-L-ala nylglycyl-L-threonyl-L-prolinamide
HC-58 EINECS 262-393-7 Elcatonin Acetate Elcatonin (Aminosuberic acid 1,7)-eel calcitonin 1,7-Dicarbacalcitonin,1-butanoic acid-26-L-aspartic acid-27-L-valine-29-L-alanine Elcatoninum [INN-Latin] Elcatonina [INN-Spanish] 1,7-Dicarbacalcitonin (salmon),1-butanoic acid-26-L-aspartic acid-27-L-valine-29-L-alanine L-Prolinamide, N-[[(2S,5S,8S,11S,14S,17S)-5-(2-amino-2-oxoethyl)-14-[(1R)-1-hydroxyethyl]-2,11-bis(hydroxymethyl)-8-(2-methylpropyl)-3,6,9,12,15,23-hexaoxo-1,4,7,10,13,16-hexaazacyclotricos-17-yl]carb ;onyl]-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-α-asparty l-L-valylglycyl-L-alanylglycyl-L-threonyl- Elcatonine [INN-French] |
Description | Elcatonin (Carbocalcitonin) is a synthetic analog of eel calcitonin. Elcatonin increases bone mineral density, inhibits bone resorption and processes a central analgesic effect[1]. |
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Related Catalog | |
In Vivo | Elcatonin (Carbocalcitonin) (20 U/kg; s.c.; 2 d after oxaliplatin administration)attenuats oxaliplatin-induced cold and mechanical allodynia in rats[2]. Animal Model: Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1] Dosage: 20 U/kg Administration: Subcutaneously; 2 d after oxaliplatin administration Result: Attenuated oxaliplatin-induced cold in rtas. |
References |
Density | 1.5±0.1 g/cm3 |
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Molecular Formula | C148H244N42O47 |
Molecular Weight | 3363.774 |
Exact Mass | 3361.799316 |
PSA | 1435.94000 |
LogP | -9.41 |
Index of Refraction | 1.659 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Hazard Codes | Xn |
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HS Code | 2937190090 |
HS Code | 2937190090 |
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