CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
NK8350000
-
CHEMICAL NAME :
-
Indene, 1-(4-dimethylaminobenzylidene)-
-
CAS REGISTRY NUMBER :
-
443-30-1
-
LAST UPDATED :
-
199712
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C18-H17-N
-
MOLECULAR WEIGHT :
-
247.36
-
WISWESSER LINE NOTATION :
-
L56 BYJ BU1R DN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
2 gm/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,771,1970 ** TUMORIGENIC DATA **
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
270 mg/kg/15D-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - ovarian tumors
-
REFERENCE :
-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 222,383,1969
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
4000 mg/kg/26W-C
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
-
REFERENCE :
-
PTEUA6 Pathologia Europaea. (Brussels, Belgium) V.1-11, 1966-76. Discontinued. Volume(issue)/page/year: 7,229,1972
|