Name | (2S)-2-amino-3-(2,6-dideuterio-4-hydroxyphenyl)propanoic acid |
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Synonyms |
[2',6'-2H2]-L-tyrosine
L-(2,6-H)Tyrosine L-Tyrosine-2,6-d2 L-4-Hydroxyphenyl-2,6-d2-alanine L-Tyrosine-d2 (phenyl-2,6-d2) L-Tyrosine-2,6-d MFCD00190464 |
Description | L-Tyrosine-d2-2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 385.2±32.0 °C at 760 mmHg |
Melting Point | >300ºC (dec.)(lit.) |
Molecular Formula | C9H9D2NO3 |
Molecular Weight | 183.201 |
Flash Point | 186.7±25.1 °C |
Exact Mass | 183.086441 |
PSA | 83.55000 |
LogP | 0.38 |
Vapour Pressure | 0.0±0.9 mmHg at 25°C |
Index of Refraction | 1.614 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Phrases | 36/37/38 |
Safety Phrases | 26-36 |
RIDADR | NONH for all modes of transport |
~99% 57746-15-3 |
Literature: Nishiyama; Oba; Ueno; Morita; Nakamura; Kainosho Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 9 p. 831 - 837 |
~% 57746-15-3 |
Literature: Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 34, # 9 p. 831 - 837 |
Precursor 2 | |
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DownStream 0 |