Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CysteamineS-phosphatesodiumsaltanalyticalstandard
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Purity: 97.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethanethiol, 2-amino-,1-(dihydrogen phosphate), sodium salt (1:1)
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Purity: 98.0%
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3724-89-8

3724-89-8 structure

Name: Ethanethiol, 2-amino-,1-(dihydrogen phosphate), sodium salt (1:1)
Chemical Name: sodium,2-aminoethylsulfanyl(hydroxy)phosphinate
CAS Number: 3724-89-8
Molecular Formula: C₂H₇NNaO₃PS
Molecular Weight: 179.11000
Catalog: Research Areas Metabolic Disease
Create Date: 2018-06-27 21:38:44
Modify Date: 2024-01-04 14:21:13
Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant[1][2].

Name	sodium,2-aminoethylsulfanyl(hydroxy)phosphinate
Synonyms	Phosphocysteamine Tsistafos MFCD00038474 Cystaphos sodium salt Tsistafos (cystafos) Cystaphos Cistaphos S-(2-Aminoethyl) thiophosphate monosodium salt EINECS 223-079-5 Cystafos

Description	Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Gainer AL, et al. Cysteamine S-phosphate hydrolysis by pure human alkaline phosphatases and by sera from patients with lymphoproliferative disorders. Cancer Res. 1982 Sep;42(9):3507-9. [2]. Besouw M, et al. Cysteamine: an old drug with new potential. Drug Discov Today. 2013 Aug;18(15-16):785-92.

Density	1.597g/cm3
Boiling Point	384.2ºC at 760mmHg
Melting Point	220ºC (dec.)(lit.)
Molecular Formula	C₂H₇NNaO₃PS
Molecular Weight	179.11000
Flash Point	186.2ºC
Exact Mass	178.97800
PSA	121.49000
LogP	0.90950

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TE6483500

CHEMICAL NAME :: Phosphorothioic acid, S-(2-aminoethyl) ester, monosodium salt

CAS REGISTRY NUMBER :: 3724-89-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C2-H7-N-O3-P-S.Na

MOLECULAR WEIGHT :: 179.12

WISWESSER LINE NOTATION :: Z2SPQO&O &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 555 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: RADOA8 Radiobiologiya. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1961- Volume(issue)/page/year: 16,249,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 505 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: RADOA8 Radiobiologiya. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1961- Volume(issue)/page/year: 16,249,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1433 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: RADOA8 Radiobiologiya. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1961- Volume(issue)/page/year: 16,249,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 806 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: RADOA8 Radiobiologiya. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1961- Volume(issue)/page/year: 16,249,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1003 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: RADOA8 Radiobiologiya. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1961- Volume(issue)/page/year: 16,249,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 358 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: RADOA8 Radiobiologiya. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1961- Volume(issue)/page/year: 16,249,1976

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	22-36/37/38
Safety Phrases	S26;S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TE6483500

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