Name | bortezomib-pinanediol |
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Synonyms |
Bortezomib pinanediol ester
2-Pyrazinecarboxamide, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]- N-{(1R)-3-Methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0]dec-4-yl]butyl}-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide Bortezomib intermediates III |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 719.5±60.0 °C at 760 mmHg |
Melting Point | 75-83ºC |
Molecular Formula | C29H39BN4O4 |
Molecular Weight | 518.455 |
Flash Point | 389.0±32.9 °C |
Exact Mass | 518.306458 |
PSA | 102.44000 |
LogP | 4.81780 |
Vapour Pressure | 0.0±2.3 mmHg at 25°C |
Index of Refraction | 1.572 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
~% 205393-22-2 |
Literature: WO2012/48745 A1, ; |
~% 205393-22-2 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 4 p. 1018 - 1029 |
~% 205393-22-2 |
Literature: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4365 - 4377 |
Precursor 9 | |
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DownStream 1 | |