4055-40-7

4055-40-7 structure

4055-40-7 structure

Name: MITOMYCIN B
Chemical Name: mitomycin B
CAS Number: 4055-40-7
Molecular Formula: C₁₆H₁₉N₃O₆
Molecular Weight: 349.339
Create Date: 2016-05-09 01:57:08
Modify Date: 2024-01-08 18:09:51

Name	mitomycin B
Synonyms	Mitomycin B 0nnDiscontinued Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-,8-carbamate Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-, (1aS,8R,8aR,8bS)- MITOMYCIN B [(1aS,8R,8aR,8bS)-8a-Hydroxy-6-methoxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate CID4209

Density	1.6±0.1 g/cm3
Boiling Point	606.6±55.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₉N₃O₆
Molecular Weight	349.339
Flash Point	320.6±31.5 °C
Exact Mass	349.127380
PSA	122.17000
LogP	0.98
Vapour Pressure	0.0±3.9 mmHg at 25°C
Index of Refraction	1.675

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CN0875000

CAS REGISTRY NUMBER :: 4055-40-7

LAST UPDATED :: 199806

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C16-H19-N3-O6

MOLECULAR WEIGHT :: 349.38

WISWESSER LINE NOTATION :: T D3 B556 BN EN JV MVTTT&J E1 GQ H1OVZ KO1 L1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 60 umol/L

REFERENCE :: CJBIAE Canadian Journal of Biochemistry. (Ontario, Canada) V.42-60, 1964-82. For publisher information, see CJBBDU. Volume(issue)/page/year: 56,296,1978

92056-68-3 structure

92056-68-3

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4055-40-7 structure

4055-40-7

Literature: Danishefsky; Ciufolini Journal of the American Chemical Society, 1984 , vol. 106, # 21 p. 6424 - 6425

Precursor 0
DownStream 3
15973-07-6 10169-34-3 74148-47-3