2242-31-1

2242-31-1 structure
2242-31-1 structure
  • Name: 1,4-BENZODIOXAN-2-METHYLAMINE, N-METHYL-
  • Chemical Name: 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-methylmethanamine
  • CAS Number: 2242-31-1
  • Molecular Formula: C10H14ClNO2
  • Molecular Weight: 215.67700
  • Create Date: 2017-07-25 22:32:38
  • Modify Date: 2024-01-29 05:16:53

Name 1-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-methylmethanamine
Synonyms Methylaminomethylbenzodioxan
882F
N-Methyl-1,4-benzodioxan-2-methylamine
1,4-BENZODIOXAN-2-METHYLAMINE,N-METHYL
Density 1.087 g/cm3
Boiling Point 261.2ºC at 760 mmHg
Molecular Formula C10H14ClNO2
Molecular Weight 215.67700
Flash Point 102ºC
Exact Mass 215.07100
PSA 30.49000
LogP 2.23870
Vapour Pressure 0.0117mmHg at 25°C
Index of Refraction 1.518
Material Safety Data Sheet

Section1. Identification of the substance
Product Name: N-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-n-methylamine, HCl
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:N-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-n-methylamine, HCl
CAS number:2242-31-1

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C10H13NO2.ClH
Molecular weight:215.7

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF3706000
CHEMICAL NAME :
1,4-Benzodioxan-2-methylamine, N-methyl-
CAS REGISTRY NUMBER :
2242-31-1
BEILSTEIN REFERENCE NO. :
0164504
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H13-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 55,15,1937
HS Code 2932999099

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Literature: JANSSEN PHARMACEUTICA N.V. Patent: WO2007/137167 A2, 2007 ; Location in patent: Page/Page column 37-38 ;

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2242-31-1

Literature: Sanchez, Isabel; Dolors Pujol, Maria; Guillaumet, Gerald; Massingham, Roy; Monteil, Andre; Dureng, Georges; Winslow, Eileen European Journal of Medicinal Chemistry, 2000 , vol. 35, # 7-8 p. 663 - 676

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2242-31-1

Literature: Soc. Usines Chim. Rhone-Poulenc Patent: DE615471 , 1933 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 713 Full Text Show Details Soc. Usines Chim. Rhone-Poulenc Patent: US2056046 , 1934 ;

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2242-31-1 structure

2242-31-1

Literature: Sanchez, Isabel; Dolors Pujol, Maria; Guillaumet, Gerald; Massingham, Roy; Monteil, Andre; Dureng, Georges; Winslow, Eileen European Journal of Medicinal Chemistry, 2000 , vol. 35, # 7-8 p. 663 - 676

~%

2242-31-1 structure

2242-31-1

Literature: McComsey, David F.; Smith-Swintosky, Virginia L.; Parker, Michael H.; Brenneman, Douglas E.; Malatynska, Ewa; White, H. Steve; Klein, Brian D.; Wilcox, Karen S.; Milewski, Michael E.; Herb, Mark; Finley, Michael F. A.; Liu, Yi; Lubin, Mary Lou; Qin, Ning; Reitz, Allen B.; Maryanoff, Bruce E. Journal of Medicinal Chemistry, 2013 , vol. 56, # 22 p. 9019 - 9030

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2242-31-1 structure

2242-31-1

Literature: Soc. Usines Chim. Rhone-Poulenc Patent: DE615471 , 1933 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 713 Full Text Show Details Soc. Usines Chim. Rhone-Poulenc Patent: US2056046 , 1934 ;
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%