50264-63-6

50264-63-6 structure

50264-63-6 structure

Name: 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
Chemical Name: 1-[(4-fluorophenyl)methyl]indazole-3-carboxylic acid
CAS Number: 50264-63-6
Molecular Formula: C₁₅H₁₁FN₂O₂
Molecular Weight: 270.258
Create Date: 2018-12-27 22:57:57
Modify Date: 2024-01-16 19:49:07

Name	1-[(4-fluorophenyl)methyl]indazole-3-carboxylic acid
Synonyms	1H-Indazole-3-carboxylic acid,1-(p-fluorobenzyl) 1-(4-fluoro-benzyl)-1H-indazole-3-carboxylic acid 1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid 1H-Indazole-3-carboxylic acid, 1-[(4-fluorophenyl)methyl]-

Density	1.3±0.1 g/cm3
Boiling Point	495.5±30.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₁FN₂O₂
Molecular Weight	270.258
Flash Point	253.4±24.6 °C
Exact Mass	270.080444
PSA	55.12000
LogP	3.16
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.640

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NK7886400

CHEMICAL NAME :: 1H-Indazole-3-carboxylic acid, 1-(p-fluorobenzyl)-

CAS REGISTRY NUMBER :: 50264-63-6

BEILSTEIN REFERENCE NO. :: 0888595

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H11-F-N2-O2

MOLECULAR WEIGHT :: 270.28

WISWESSER LINE NOTATION :: T56 BNNJ B1R DF& DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 377 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 19,778,1976

HS Code	2933990090

1185287-50-6 structure

1185287-50-6

~97%

50264-63-6 structure

50264-63-6

Literature: Pfizer Inc. Patent: US2011/28447 A1, 2011 ; Location in patent: Page/Page column 33-34 ;

43120-28-1 structure

43120-28-1

~%

50264-63-6 structure

50264-63-6

Literature: Pfizer Inc. Patent: US2011/28447 A1, 2011 ;

459-46-1 structure

459-46-1

~%

50264-63-6 structure

50264-63-6

Literature: Pfizer Inc. Patent: US2011/28447 A1, 2011 ;

Precursor 3
1185287-50-6 43120-28-1 459-46-1
DownStream 1
1185282-01-2

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%