957209-68-6

957209-68-6 structure

Name: NVP-QAV-572
Chemical Name: Urea, N-[2-[2-(2-fluoroethyl)-2H-tetrazol-5-yl]ethyl]-N'-[5-[3-fluoro-4-(methylsulfonyl)phenyl]-4-methyl-2-thiazolyl]
CAS Number: 957209-68-6
Molecular Formula: C₁₇H₁₉F₂N₇O₃S₂
Molecular Weight: 471.50500
Catalog: Research Areas Cancer
Create Date: 2018-05-12 08:00:00
Modify Date: 2024-01-11 12:38:23
NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM.

Name	Urea, N-[2-[2-(2-fluoroethyl)-2H-tetrazol-5-yl]ethyl]-N'-[5-[3-fluoro-4-(methylsulfonyl)phenyl]-4-methyl-2-thiazolyl]
Synonyms	nvp-qav-572

Description	NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM.
Related Catalog	Research Areas >> Cancer
Target	PI3K:10 nM (IC50)
In Vitro	NVP-QAV-572 (Example 8) is useful in the treatment of conditions which are mediated by the activation of the Pi3 kinase enzymes, particularly inflammatory or allergic conditions[1].
References	[1]. Emma Budd, et al. 5-phenyl-thiazol-2-yl-urea derivatives and use as PI3 kinase inhibitors. US 7998990 B2.