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957229-52-6

957229-52-6 structure
957229-52-6 structure
  • Name: 5β-Dutasteride
  • Chemical Name: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aS)
  • CAS Number: 957229-52-6
  • Molecular Formula: C27H30F6N2O2
  • Molecular Weight: 528.53000
  • Catalog: Research Areas Others
  • Create Date: 2018-11-24 22:37:49
  • Modify Date: 2024-01-19 09:55:32
  • 5β-Dutasteride is the S configuration of Dutasteride. 5β-Dutasteride is a potent inhibitor of both 5 alpha-reductase isozymes[1].

Name 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aS)
Synonyms 5β-Dutasteride
5-Beta-Dutasteride
Dutasteride Impurity 2
Description 5β-Dutasteride is the S configuration of Dutasteride. 5β-Dutasteride is a potent inhibitor of both 5 alpha-reductase isozymes[1].
Related Catalog
References

[1].  Lazier CB, et al. Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line. Prostate. 2004 Feb 1;58(2):130-44.

Density 1.303±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point 620.3±55.0 °C (760 mmHg)
Molecular Formula C27H30F6N2O2
Molecular Weight 528.53000
Exact Mass 528.22100
PSA 58.20000
LogP 6.97790