147332-48-7

147332-48-7 structure

Name: ICI D1542
Chemical Name: 6-[2-[2-(4-methyl-3-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid
CAS Number: 147332-48-7
Molecular Formula: C₂₅H₃₀N₂O₇
Molecular Weight: 470.51500
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2017-05-13 04:21:32
Modify Date: 2024-02-01 20:53:25
ICI D1542 is a selective and potent inhibitor of thromboxane A2 (TXA2) synthase and the thromboxane A2 receptor (TP-receptor). ICI D1542 is effective at preventing thrombus formation by redirection of arachidonic acid metabolism[1].

Name	6-[2-[2-(4-methyl-3-nitrophenoxy)propan-2-yl]-4-pyridin-3-yl-1,3-dioxan-5-yl]hex-4-enoic acid
Synonyms	ici-d 1542 zd 1542

Description	ICI D1542 is a selective and potent inhibitor of thromboxane A2 (TXA2) synthase and the thromboxane A2 receptor (TP-receptor). ICI D1542 is effective at preventing thrombus formation by redirection of arachidonic acid metabolism[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. S J McAuliffe, et al. Redirection of arachidonic acid metabolism by ICI D1542: effects on thrombus formation in the coronary artery of the anaesthetized dog. r J Pharmacol. 1993 Apr;108(4):901-6.