921-62-0
921-62-0 structure
- Name: 6-Phosphogluconic acid
- Chemical Name: 6-phospho-D-gluconic acid
- CAS Number: 921-62-0
- Molecular Formula: C6H13O10P
- Molecular Weight: 276.135
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-07-23 12:32:04
- Modify Date: 2024-01-02 14:41:25
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6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite[1][2].
| Name | 6-phospho-D-gluconic acid |
|---|---|
| Synonyms |
6-PHOSPHOGLUCONIC ACID BARIUM SALT
EINECS 213-069-9 6-Phosphogluconate Barium Salt Hydrate MFCD00066440 6-O-Phosphonohexonic acid Hexonic acid, 6-(dihydrogen phosphate) |
| Description | 6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | 6-Phosphogluconic acid (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate[1]. |
| References |
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 774.8±70.0 °C at 760 mmHg |
| Molecular Formula | C6H13O10P |
| Molecular Weight | 276.135 |
| Flash Point | 422.4±35.7 °C |
| Exact Mass | 276.024628 |
| PSA | 406.56000 |
| LogP | -3.25 |
| Vapour Pressure | 0.0±6.0 mmHg at 25°C |
| Index of Refraction | 1.623 |
| Storage condition | 20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H332 |
| Precautionary Statements | P261-P301 + P312 + P330-P304 + P340 + P312 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R20/22 |
| Safety Phrases | 28 |
| RIDADR | UN 1564 6.1/PG 3 |
| Packaging Group | III |
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921-62-0 |
| Literature: Biochemical Journal, , vol. 25, p. 323,329 Biochemische Zeitschrift, , vol. 292, p. 289 |
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| Literature: Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, , vol. 35, # 5 p. 427 - 430 |
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| Literature: Biochemical Journal, , vol. 25, p. 323,329 |
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| Literature: Biochemical Journal, , vol. 25, p. 323,329 |
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| Literature: Biochemical Journal, , vol. 25, p. 323,329 |
