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35482-50-9

35482-50-9 structure
35482-50-9 structure
  • Name: 5-METHYL-2-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-2-CYCLOHEXEN-1-YL]-1,3-BENZENEDIOL
  • Chemical Name: 5-methyl-2-[(6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]benzene-1,3-diol
  • CAS Number: 35482-50-9
  • Molecular Formula: C17H22O2
  • Molecular Weight: 258.355
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
  • Create Date: 2016-06-29 08:10:49
  • Modify Date: 2024-01-10 00:49:34
  • Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations[1][2].
Name 5-methyl-2-[(6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]benzene-1,3-diol
Synonyms Cannabidiorcol
Cannabidiorocol
1,3-Benzenediol, 5-methyl-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-
2-[(1R,6R)-6-Isopropenyl-3-methyl-2-cyclohexen-1-yl]-5-methyl-1,3-benzenediol
O 1821
Description Cannabidiorcol (CBDO, CBD-C1, O-1821) is related to cannabidiol, with the pentyl side chain shortened to a methyl group. Cannabidiorcol has low affinity for cannabinoid receptors (CBs) and is an agonist of the transient receptor potential channel (TRP channel), through which it produces antiinflammatory effects, but can also promote tumorigenesis at high concentrations[1][2].
Related Catalog
Target

AChE:4.61 mM (Ki)

References

[1]. Teresina Laragione, et al. Combination therapy of a TRPV2 agonist with a TNF inhibitor achieves sustained suppression of disease severity and reduced joint damage. Clin Exp Immunol. 2023 Mar; 211(3): 233–238.

[2]. Rongqi Huang, et al. Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma. Br J Cancer. 2022 Nov 1; 127(8): 1424–1439.

Density 1.1±0.1 g/cm3
Boiling Point 414.3±45.0 °C at 760 mmHg
Molecular Formula C17H22O2
Molecular Weight 258.355
Flash Point 192.3±23.3 °C
Exact Mass 258.161987
PSA 40.46000
LogP 4.91
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.565
Precursor  2

DownStream  0


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title: CAS No. 35482-50-9 | Chemsrc address: https://www.chemsrc.com/en/baike/80289.html

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