347884-61-1

347884-61-1 structure

Name: Alloferon
Chemical Name: alloferon 1
CAS Number: 347884-61-1
Molecular Formula: C₅₂H₇₅N₂₂O₁₆
Molecular Weight: 1264.29000
Catalog: Research Areas Cancer
Create Date: 2018-07-02 18:22:40
Modify Date: 2024-01-07 17:12:53
Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera)[1][2][3].

Name	alloferon 1
Synonyms	H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH Alloferon HIS-GLY-VAL-SER-GLY-HIS-GLY-GLN-HIS-GLY-VAL-HIS-GLY

Description	Alloferon 1 is an antiviral and antitumoral peptide. Alloferon 1 stimulates natural cytotoxicity of human peripheral blood lymphocytes. Alloferon 1 also induces IFN synthesis, and enhances antiviral and antitumor resistance in mice. Alloferon 1 also shows anti-inflammatory activity in λ-carrageenan-induced paw edema model. Alloferon 1 can be isolated from the blood of the blow fly Calliphora vicina (Diptera)[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Chernysh S, et al. Antiviral and antitumor peptides from insects. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12628-32. [2]. Zhang X, et al. Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice. Sci Rep. 2022 Oct 6;12(1):16689.