35218-75-8

35218-75-8 structure
35218-75-8 structure

Name tpps
Synonyms tetraphenylporphinesulfonate
MFCD00070632
tpps4
(Tetraphenylporphyrin Tetrasulfonic Acid Hydrate)
4,4',4'',4'''-(5,10,15,20-Porphyrintetrayl)tetrabenzenesulfonic acid
Benzenesulfonic acid, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-
meso-Tetraphenylporphine-4,4',4
meso-tetraphenylporphine-4,4',4'',4'''-tetrasulfonic acid
TSPP
5,10,15,20-Tetrakis(4-sulfophenyl)porphyrin Hydrate
5,10,15,20-tetraphenyl-21H,23H-perphine-4,4',4'',4'''-tetrasulfonic acid
4,4',4'',4'''-porphyrin-5,10,15,20-tetrayltetrabenzenesulfonic acid
Description TPPS can be used as a non-cytotoxic probe for detecting tumor location[1].
Related Catalog
In Vitro TPPS (0-20 μg/mL) shows no toxicity in Vero and HEp-2 cells in vitro and predominantly locates in the soluble and protein fractions in cells[1].
In Vivo TPPS4 shows the highest tumor to tissue ratios after 96 hours injection with a dose dependent manner[2]. TPPS4 appears to be cleared through the kidneys and absolute concentrations there are reduced with increasing time after injection[2].
References

[1]. Austen JD, et al. Intracellular localization of meso-Tetra(p-sulfophenyl)porphine: a potential tumor localizing agent. Cancer Treat Rep. 1978 Apr;62(4):511-8.

[2]. https://pubmed.ncbi.nlm.nih.gov/201378/

Density 1.6±0.1 g/cm3
Molecular Formula C44H30N4O12S4
Molecular Weight 934.989
Exact Mass 934.074280
PSA 307.30000
LogP 5.01
Index of Refraction 1.724
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DB7339000

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35218-75-8 structure

35218-75-8

Literature: Journal of the Chemical Society, Faraday Transactions, , vol. 89, # 3 p. 495 - 502

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35218-75-8 structure

35218-75-8

Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 12.1 p. 1987 - 1994 Zhurnal Organicheskoi Khimii, , vol. 28, # 12 p. 2464 - 2472